Results

Generally, RABBIT shows biologic DMARDs to be effective, safe and well tolerated in daily rheumatologic care. Used by experienced rheumatologists, they are a safe treatment option for patients with rheumatoid arthritis, who do not respond adequately to non-biologic DMARDs.


In practice, biologic DMARDs are not prescribed until non-biologic DMARDs fail or are not tolerated. That means that patients for whom biologic DMARDs are indicated differ systematically from patients who are treated with non-biologic DMARDs. Therefore, highly sophisticated statistical methods are required to compare patients on biologic and non-biologic DMARDs. Here, we will give a short insight into our published results.

Enrolment

Update: January 2nd, 2019; enrolled patients: 17,991

Amgevita┬« (Adalimumab)     2
Benepali┬« (Etanercept)  515
Cimzia┬« (Certolizumab)   862
Enbrel® (Etanercept)2856
Erelzi┬« (Etanercept)  121
Flixabi┬« (Infliximab)      1
Humira® (Adalimumab)2895
Hyrimoz┬« (Adalimumab)     4
Inflectra┬« (Infliximab)    16
Kevzara┬« (Sarilumab)    44
Kineret┬« (Anakinra)    89
MabThera┬« (Rituximab) 1463
Olumiant┬« (Baricitinib)   212
Orencia┬« (Abatacept)   737
Remicade┬« (Infliximab)   762
Remsima┬« (Infliximab)      9
Rixathon┬« (Rituximab)      3
RoActemra┬« (Tocilizumab) 1284
Simponi┬« (Golimumab)   433
Xeljanz┬« (Tofacitinib)   164
Control Group 5519